TitleA tail goes viral by forming an anchor and a tether.
Publication TypeJournal Article
Year of Publication2021
AuthorsBarbar E, Estelle A
JournalStructure
Volume29
Issue8
Pagination783-786
Date Published2021 08 05
ISSN1878-4186
Abstract

In this issue of Structure, Aiyer et al. (2021) report NMR structures of BET:MLV IN complexes, highlighting a role for the disordered tail domain of MLV IN in viral integration. These studies expand the understanding of molecular recognition polymorphism in BET complexes and offer insight into cancer and antiviral therapeutics.

DOI10.1016/j.str.2021.07.004
Alternate JournalStructure
PubMed ID34358464