|Title||Regioselective Synthesis of Substituted Carbazoles, Bicarbazoles, and Clausine C.|
|Publication Type||Journal Article|
|Year of Publication||2021|
|Authors||Points GL, Beaudry CM|
|Date Published||2021 09 03|
Substituted carbazoles are efficiently constructed from 3-triflato-2-pyrones and alkynyl anilines. Multiple substituents are tolerated on the carbazole, and complete control of regiochemistry is observed. Complicated and sterically congested substitution patterns are produced. This strategy is also used to prepare substituted bicarbazoles and related biaryls. Finally, the method was showcased in a synthesis of the carbazole natural product clausine C.
|Alternate Journal||Org Lett|