TitleRegioselective Synthesis of Benzofuranones and Benzofurans.
Publication TypeJournal Article
Year of Publication2021
AuthorsZhang X, Beaudry CM
JournalJ Org Chem
Volume86
Issue9
Pagination6931-6936
Date Published2021 05 07
ISSN1520-6904
KeywordsAlkenes, Benzofurans, Catalysis, Molecular Structure
Abstract

Reaction of 3-hydroxy-2-pyrones with nitroalkenes bearing ester groups gives benzofuranones. The reaction allows regioselective preparation of the benzofuranones with programmable substitution at any position. Complex substitution patterns are readily created. The substituted benzofuranones can be converted to substituted benzofurans.

DOI10.1021/acs.joc.1c00341
Alternate JournalJ Org Chem
PubMed ID33852303