Title | Regioselective Synthesis of Benzofuranones and Benzofurans. |
Publication Type | Journal Article |
Year of Publication | 2021 |
Authors | Zhang X, Beaudry CM |
Journal | J Org Chem |
Volume | 86 |
Issue | 9 |
Pagination | 6931-6936 |
Date Published | 2021 05 07 |
ISSN | 1520-6904 |
Keywords | Alkenes, Benzofurans, Catalysis, Molecular Structure |
Abstract | Reaction of 3-hydroxy-2-pyrones with nitroalkenes bearing ester groups gives benzofuranones. The reaction allows regioselective preparation of the benzofuranones with programmable substitution at any position. Complex substitution patterns are readily created. The substituted benzofuranones can be converted to substituted benzofurans. |
DOI | 10.1021/acs.joc.1c00341 |
Alternate Journal | J Org Chem |
PubMed ID | 33852303 |