19F NMR in Drug Discovery
NMR has held an important position in drug discovery for a number of years. Whether it is in protein structure determination, fragment or ligand based drug discovery, structure elucidation and verification or even in the drug development or production, NMR has been able to provide answers to problems in all these areas. The talk will focus on the currently interesting applications in drug discovery. These will include aspects of FBDD or LBDD and the use of 19F in these methods.
Clemens Anklin got his Ph.D. in organometallic chemsitry at the Swiss Federal Institute of Technology (ETH) in Zurch, Switzerland in 1984. He joined Bruker as an applications scientist the same year. In 1988 he moved to the United States and since occupied various positions in the NMR applications department. He currently holds the position of Vice President for NMR applicaitons and training with Bruker Biospin.